The episode features Kat Lazo, a 25-year-old self-described "proud lesbian" from Las Vegas, Nev., who lives with a form of stomach cancer that keeps her from enjoying her favorite foods. Through her determination to live life colorfully, she consistently inspires people with her vibrant personality and zest for life. Also featured in the episode is Isabel Bueso, of Concord, Calif., an aspiring sociologist born with a very rare medical condition named Mucopolysaccharidosis VI (MPS VI). Raised knowing that she would not live past 20, Isabel, now 21, continues to research MPS VI and regularly organizes events to build awareness.